Andrea Hupfeld
Curriculum vitae
Andrea Hupfeld (née Kneuttinger) is a research group leader in Biochemistry at the University of Regensburg. Her group focuses on the engineering of photocontrol in enzymes by using a combined enzymology, chemical biology, and protein engineering approach.
In 2010, she obtained her Master degree in Biochemistry and was awarded with the Jürgen-Manchot prize for characterizing a DNA repair enzyme. Motivated by this interdisciplinary work at the interface of enzymology and organic chemistry, she continued the project in her doctorate with Thomas Carell at the Ludwig-Maximilians-University of Munich until 2014.
Driven by the desire to acquire additional professional expertise and life experience outside research, she honed her teaching skills both as a Science teacher in Southampton (England) and a lecturer on Scientific English in Regensburg (Germany), as well as her leadership skills by qualifying as project management specialist.
In 2016 Andrea resumed her career in research as a PostDoc with Reinhard Sterner at the University of Regensburg, where she achieved to photocontrol enzyme activity and allostery reversibly and with high light-regulation factors by the incorporation of photo-responsive unnatural amino acids.
In 2020 she founded her own research group and she finished her habilitation in June 2025.

Education
2020 – 2025 | HABILITATION IN BIOCHEMISTRY University of Regensburg |
2010 – 2014 | DISSERTATION IN ORGANIC CHEMISTRY Ludwig-Maximilians-University Munich |
2008 – 2010 | “MASTER OF SCIENCE” IN BIOCHEMISTRY Technical University Munich |
2005 – 2008 | “BACHELOR OF SCIENCE” IN BIOCHEMISTRY Technical University Munich |
Career
present | GROUP LEADER Institute of Biophysics and Physical Biochemistry, University of Regensburg |
2016 – 2019 | POSTDOC Institute of Biophysics and Physical Biochemistry, University of Regensburg |
2015 – 2016 | LECTURER Department of Chemistry and Pharmacy, University of Regensburg |
2014 – 2015 | TEACHER Science Department, Wildern School Southampton |
Current members
Enrico Hupfeld

PostDoc
Email (opens your email program)
Phone: +49-941-943-3339
Room: E3_1.303
Member since: Dec 2024
Caroline Hiefinger

PhD student
Email (opens your email program)
Phone: +49-941-943-1639
Room: E3_1.307
Member since: Sep 2020
Sabrina Mandl

PhD student
Email (opens your email program)
Phone: +49-941-943-1639
Room: E3_1.307
Member since: Sep 2020
Mona Wieland

[Translate to English:]
PhD student
Email (opens your email program)
Phone: +49-941-943-3041
Room: E3_1.305
Member since: Dec 2020
Verena Pape

Mila
Mascot
Room: E3_1.307
Member since: Sep 2020
Alumni
We thank all former colleagues who contributed to our vision of engineering photocontrol in enzymes.
Master Students | Publications | |
---|---|---|
2024 - 2025 | Elena Adlmanninger | [21] |
2022 - 2023 | Barbara Maiwald (née Hufnagl) | [21] |
2021 - 2022 | Michael Bartl | |
2021 | Johanna Rein | [19] |
2020 - 2021 | Fjoralba Zeqiri | [20] |
2020 - 2021 | Barbara Germscheid (née Gaim) | [11, 19] |
2018 – 2019 | Stefanie Zwisele | [11] |
2017 – 2018 | Thomas Kinateder | [11, 13] |
2017 – 2018 | Philipp Bittner | [10, 21] |
2016 – 2017 | Martin Winter | [9] |