Human Genetics

Prof. Dr Dr med. Davor Lessel

Link to Human Genetics at the University Hospital (external link, opens in a new window)

Application to the Human Genetics module

Registration by 31st of July: Dr Fabiola Biasella (Fabiola.Biasella@klinik.uni-regensburg.de)

Note on registration for the human genetics module:

The high demand for places in the Master's module 'Human Genetics' makes the following procedure necessary: Please formally apply by 31 July of each year for the coming winter semester (by e-mail to Fabiola.Biasella@klinik.uni-regensburg.de, subject line: Elective Module Human Genetics). Please enclose a short curriculum vitae with your application, including a list of written exams and examination results. We may then invite you to a short interview. You will receive binding notification by the end of July at the latest as to whether you can be accepted onto the module. We ask you to inform us by the end of August whether you would like to accept the place or not. All unfilled places will then be allocated in a succession procedure by mid-September.

Application to the Human Genetics module

Due to the high demand of students to the "Human Genetics" module, a selection process takes place. Please send your application by e-mail to Fabiola.Biasella@klinik.uni-regensburg.de with the Subject heading: Wahlmodul Humangenetetik until July 31 if you want to start the module in the upcoming winter semester. The application should include a short curriculum vitae and a grade transcript. If needed, you will be invited to a short interview. Acceptance to the module will be communicated at the latest at the end of July. We request that you let us know until the end of August if you will take the module or not. Should there be free places left, these will be allotted until mid-September.

TM Human Genetics

BIO-M-TM-HG

Detailed module description - pdf (external link, opens in a new window)

Prof. Dr Dr med. Davor Lessel

Module contents
Advanced Human Genetics Lecture on advanced topics of human genetics including state of the art research and therapeutic approaches with a strong focus on genetic variation in health and disease. Topics include but are not limited to Major developments in human genetics research in recent years Major advances in identifying disease genes (monogenic and multifactorial) Complex data in human genetics Novel insights into population genetics In-depth considerations to monogenic and multifactorial disorders Targeted treatment strategies for genetic disorders Advanced tumour genetics Epigenetics as an emerging field in human genetics State of the art diagnostics/ medical genetics /personalised genetic counselling Applied Human Genetics including Course Work This course provides a deeper understanding of the impact of molecular biology and genetics on modern medicine and the connection between basic research, medical knowledge and an improved patient management. Concepts will be accompanied by theoretical introductions followed by a guided experimental lab course. Detailed analysis of human and molecular genetics with particular focus on the variability of the human genome. Introduction to basic and advanced methodologies, e.g. DNA sequencing technologies according to Sanger, next generation sequencing for gene panels, exomes and whole genomes Principals and specifics in modern DNA diagnostics From raw data to interpretation of genetic variants First insight into bioinformatics and genetic statistics Eukaryotic cell culture and heterologous gene expression Induced pluripotent stem cell technology and development of model systems in the dish CRISPR-Cas mediated genomics editing mRNA expression analysis by quantitative real time reverse transcriptase PCR Applications in confocal laser scanning microscopy Mouse models in human genetics research Literature Seminar in Human Genetics In this weekly seminar current peer reviewed publications in the field of human genetics are presented and discussed in-depth. Students give a brief power point presentation, followed by an interactive discussion with fellow students and staff of the Institute of Human Genetics.
Module components
1. Lectures Advanced Human Genetics (formerly called "Humangenetics I") Applied Human Genetics Lecture and Lab Course (formerly called "Humangenetics II") Please note that the written exam for Advanced Human Genetics is in German language only! Course work for the Applied Human Genetics part has to be conducted in English. 2.Human Genetics Literature Seminar (EXA 56121)
Module examination
30 min oral examination (graded); in English by request. Information on the topics and how to enrol for the oral examination (Oct 2021)- pdf! (external link, opens in a new window)

PM Human Genetics

BIO-M-PM-HG

Detailed module description - pdf (external link, opens in a new window)

Prof. Dr Dr med. Davor Lessel (link to research group (external link, opens in a new window))

Module contents
Standard laboratory techniques in molecular biology and genetics; in-depth experimental applications including standard and advanced methodologies Knowledge of and familiarisation with public databases and software relevant to molecular genetics Application of cell culture and animal model systems to address clinically relevant questions Presentation and discussion of own data generated experimentally Communication of scientific results (lectures, posters, protocols) Overview of research areas in human genetics and advanced knowledge of experimental approaches in the field of molecular medical research
Module components
Laboratory course (6 weeks) with seminar: Human Genetics
Module examination
Portfolio examination (graded)

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